The article by Dr Nesse is a fine recap of issues as to possible adaptive aspects of depression.1 It heralds to a large audience that there is more to come as evolutionary science continues to reform and integrate studies in psychopathology. Nesse, who has already done so much to foster the fruition of darwinian psychology and medicine, has done us another good turn.2,3 Yet, for all the growth of "evolutionary psychology" thus far, it has yet to come to grips with genetic science.4 In this context, the lack of reference to evolutionary epidemiology as an operationalized mode for precise assessments is a regrettable omission.4
Wilson DR. Depression Is an Adaptation. Arch Gen Psychiatry. 2001;58(11):1086–1087. doi:
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