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Letters to the Editor
May 2002

Antiobsessional Effect of Risperidone Add-On Treatment in Serotonin Reuptake Inhibitor–Refractory Obsessive-Compulsive Disorder May Be Dose-Dependent

Arch Gen Psychiatry. 2002;59(5):472. doi:

In their recent article, McDougle et al1 concluded that patients with obsessive-compulsive disorder (OCD) refractory to serotonin reuptake inhibitor (SRI) monotherapy may respond to a mean ± SD low dose of risperidone (2.2 ± 0.7 mg) added to SRI treatment. However, the observed relationship between low doses of risperidone and its antiobsessional effect needs further evaluation.

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