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Letters to the Editor
November 2004

Does Glial Asthenia Predispose to Schizophrenia?

Arch Gen Psychiatry. 2004;61(11):1170. doi:10.1001/archpsyc.61.11.1170

Glial cells have been grossly neglected in schizophrenia research.1 Hopefully, the publication of the oligodendrocytehypothesis by Davis et al2 in the May 2003issue of the ARCHIVES and their excellent review of the supportingevidence will change the situation. Oligodendrocytes produce myelin and, togetherwith astrocytes and microglia, were formerly thought to be merely glia (“glue”)of the brain.

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