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Letters to the Editor
March 2008

Environmental Risk Factors and Attention-Deficit/Hyperactivity Disorder Symptoms

Arch Gen Psychiatry. 2008;65(3):356-357. doi:10.1001/archpsyc.65.3.356-b

The article by Laucht et al1 aims to elicit the independent and combined effects of the dopamine transporter gene (DAT1) 40–base pair (bp) variable number of tandem repeats (VNTR) polymorphism and psychosocial adversity on attention-deficit/hyperactivity disorder (ADHD) symptoms in 15-year-olds from a high-risk community sample. In addition, 4 further genetic variants in linkage disequilibrium with the DAT1 40-bp VNTR polymorphism were assessed.

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