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January 1960

Psychological Studies on Effects of Chemosurgery of the Basal Ganglia in Parkinsonism: I. Intellectual Functioning

Author Affiliations

New York
From the Departments of Psychology and Neurosurgery, St. Barnabas Hospital for Chronic Diseases and the New York University-Bellevue Medical Center.

AMA Arch Gen Psychiatry. 1960;2(1):22-32. doi:10.1001/archpsyc.1960.03590070024004

It is the purpose of this report to present findings on the immediate and longe-range postoperative intellectual functioning of a large series of patients who underwent chemopallidectomy and Chemothalamectomy1-6 for the relief of Parkinsonian symptoms. The findings are based on the Wechsler-Bellevue Intelligence Scale, Form I.

Background  The following review of the literature on the intellectual effects of brain injury, disease, and surgery will emphasize, particularly, those utilizing the Wechsler-Bellevue Scale. Allen, in a series of studies on both the brain-injured and the brain-diseased,7-10 concludes that both groups demonstrate “a depressed level of efficiency” in intellectual functioning, faring more poorly on performance items than on verbal ones. Their primary handicap is in the area of motor manipulation. Most resistant to organic inroads were the subtests of information, comprehension, and vocabulary. Other Wechsler studies on the organically impaired report like findings. Goldman et al.

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