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This volume represents a collection of lectures given during the Pittsburgh Bicentennial year, most of them at a two-day conference on Experimental Psychiatry at the Western Psychiatric Institute, March, 1959. In reviewing a book such as this, generally it is not feasible or appropriate to focus on its individual contributions. In this case it would be particularly difficult to select chapters for individual attention (either on the basis of authority and eminence of the authors, or on the basis of the interest and importance of the content). The editor is to be congratulated not only for having assembled a group of speakers (and authors) who present a remarkably fine and detailed cross-section of current American experimental psychiatry, but also for having inspired (or otherwise evoked) contributions from them that in most instances belong with the best of their other publications. In my opinion, the book is unusually successful in this