EVALUATION of the role of the adrenal cortex in the response of man to stressful situations has long been a problem of major interest to investigators. Early the effects of relatively well defined and isolated environmental events were studied. These included studies of auto race drivers,1 college 0arsmen,2 medical students taking final exams,3 and patients prior to cardiac and pulmonary surgery.4 Initially the stress of the event itself was regarded as the only significant variable against which the subjects physiological response was measured. The degree of stress which such events provided for the subjects under study was based entirely on subjective estimates by the investigators. Subsequent studies, especially those of Wolff,5 Fox,6 and Sachar,7 modified this approach by suggesting the importance of individual difference in the psychological and physiological handling of threatening events in the environment,
Bourne PG, Rose RM, Mason JW. 17-OHCS Levels in CombatSpecial Forces "A" Team Under Threat of Attack. Arch Gen Psychiatry. 1968;19(2):135–140. doi:10.1001/archpsyc.1968.01740080007002
Customize your JAMA Network experience by selecting one or more topics from the list below.