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March 1972

Vertical-Chamber Confinement of Juvenile-Age Rhesus Monkeys: A Study in Experimental Psychopathology

Arch Gen Psychiatry. 1972;26(3):223-228. doi:10.1001/archpsyc.1972.01750210031006

Male rhesus monkeys (Macaca mulatta) 3 years of age were studied socially before and after ten weeks of confinement in a vertical-chamber apparatus designed to facilitate production of psychopathological disturbance. This study represents an initial effort to move beyond the use of young monkeys in a depression research program. Chamber confinement results in a significant increase in contact clinging between animals and a decrease in locomotion following removal from the apparatus. These behavior patterns are very atypical of laboratory-reared rhesus monkeys of this age and may represent a maturational regression induced by social means.