Four rhesus monkeys which were subjected to partial social isolation during the first 11 months of life and which had consistently exhibited patterns of grossly abnormal behavior during the 1½ years prior to the current study were treated with chlorpromazine.
Three of the four subjects showed significant decreases in their self-disturbance behaviors on 7.5 mg/day of chlorpromazine given as the liquid concentrate by nasogastric intubation. The fourth subject showed no change. Plasma chlorpromazine levels confirmed absorption of the drug in all subjects.
McKinney WT, Young LD, Suomi SJ, Davis JM. Chlorpromazine Treatment of Disturbed Monkeys. Arch Gen Psychiatry. 1973;29(4):490–494. doi:10.1001/archpsyc.1973.04200040042007
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