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March 1974

Tardive Dyskinesia and Drug Therapy in Geriatric Patients

Arch Gen Psychiatry. 1974;30(3):341-343. doi:10.1001/archpsyc.1974.01760090055009

The main objective of this paper was to relate tardive dyskinesia to the total intake of neuroleptics.

The data were based on a selected sample of geriatric patients, on accurate and complete information on chemotherapy, and on three neurological examinations.

A 7-point rating scale was used to distinguish drug-induced from spurious motor abnormalities. Two statistical approaches demonstrated that the risk of oral dyskinesia increases with the exposure to neuroleptics.