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May 1975

Akinesia: A Poorly Recognized Drug-Induced Extrapyramidal Behavioral Disorder

Author Affiliations

From the Long Island Jewish-Hillside Medical Center, Hillside Division, PO Box 38, Glen Oaks, New York.

Arch Gen Psychiatry. 1975;32(5):672-674. doi:10.1001/archpsyc.1975.01760230138011

Akinesia is an extrapyramidal behavioral side-effect of antipsychotic medication characterized by a lessening of spontaneity, paucity of gestures, diminished conversation, and apathy. It can be easily confused with depression, demoralization, and residual schizophrenic defect. Studies of the value of maintenance antiparkinson medication usually overlook this common syndrome. We present eight case histories to illustrate this condition.