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January 1979

Prognostic Implications of Six Alternative Definitions of Schizophrenia

Author Affiliations
From the University Department of Psychiatry, Royal Edinburgh Hospital, Edinburgh, Scotland.
Arch Gen Psychiatry. 1979;36(1):25-31. doi:10.1001/archpsyc.1979.01780010031002

• The ability of six different operational definitions of schizophrenia to identify prospectively patients whose eventual prognosis would be poor was studied using data from a six-year follow-up of a series of 134 patients with functional psychoses. All six definitions were more successful at predicting a poor symptomatic outcome than a poor social outcome. Spitzer's Research Diagnostic Criteria, Carpenter's flexible criteria, and Langfeldt's criteria predicted a poor outcome as well as the original clinical diagnoses and were considerably better than the New Haven criteria, Schneider's first rank symptoms, or the computer program Catego.