• Linkage between protanopia and deuteranopia and bipolar manic-depressive illness is demonstrated in a sample of eight informative families ascertained in Brussels. Genetic heterogeneity of bipolar affective disorders is also shown in the present sutdy. These results add new evidence to the hypothesis of X-linked dominant genetic transmission of affective liability in a subgroup of patients with bipolar affective disorders.
Mendlewicz J, Linkowski P, Guroff JJ, Van Praag HM. Color Blindness Linkage to Bipolar Manic-Depressive IllnessNew Evidence. Arch Gen Psychiatry. 1979;36(13):1442–1447. doi:10.1001/archpsyc.1979.01780130060007