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January 1980

Lithium Transport Across the RBC Membrane: A Study of Genetic Factors

Author Affiliations

From the Department of Psychiatry, University of Chicago (Drs Dorus, Pandey, and Davis); and the Department of Research, Illinois State Psychiatric Institute, Chicago (Drs Pandey, Shaughnessy, and Davis).

Arch Gen Psychiatry. 1980;37(1):80-81. doi:10.1001/archpsyc.1980.01780140082009

• The measurement of the ratio of RBC to plasma lithium ion levels in vitro in 291 members of 120 families indicated that genetic factors contribute substantially to interindividual variability in the lithium ion distribution across the RBC membrane. These factors affect the lithium-sodium ion exchange system that determines the lithium ion distribution.

Arch Gen Psychiatry 37:80-81,1980)

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