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June 1980

Deviant Eye Tracking in Twins Discordant for Psychosis: A Replication

Author Affiliations

From the Department of Psychology and Social Relations and the Mailman Research Center, McLean Hospital, Harvard University, Cambridge, Mass (Dr Holzman); the Institute for Behavorial Sciences in Medicine, University of Oslo (Dr Kringlen); the Illinois State Psychiatric Institute, Chicago (Dr Levy); and the Department of Statistics, University of Chicago (Dr Haberman).

Arch Gen Psychiatry. 1980;37(6):627-631. doi:10.1001/archpsyc.1980.01780190025002

• An earlier study of smooth-pursuit eye movements (SPEMs) in monozygotic (MZ) and dizygotic (DZ) twins discordant for functional psychosis reported high concordance of pursuit abnormalities in MZ pairs and moderate concordance in DZ pairs. That study was repeated with younger pairs of twins and with some quantitative refinements in scoring. Results show the same levels of concordance for pursuit dysfunctions, thus replicating the earlier study. The data support an interpretation of genetic factors contributing to variability in SPEMs.

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