• A questionnaire study of drug use and life-style among college seniors, previously performed in 1969, was repeated at the same college in 1978 with identical methods. Moderate increases in marijuana use were found; cocaine use had increased dramatically; most other drug use changed only slightly. Differences between users and nonusers, already modest in 1969, had narrowed further by 1978: users and nonusers were indistinguishable on grades, athletics, other college activities, career plans, and subjective alienation. Only heterosexual activity and visits to a psychiatrist still distinguish users from nonusers.