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May 1983

Premenstrual Depressive Changes: Value of Differentiation

Author Affiliations

From the Division of Biological Psychiatry, Department of Psychiatry, Albert Einstein College of Medicine, New York (Dr Halbreich), and the Research Assessment and Training Unit, Department of Psychiatry, Columbia University College of Physicians and Surgeons and the New York State Psychiatric Institute, New York (Drs Endicott and Nee).

Arch Gen Psychiatry. 1983;40(5):535-542. doi:10.1001/archpsyc.1983.01790050061007

• Premenstrual depressive changes and differential correlates of specific subtypes of premenstrual dysphoria vary. Our data support two basic assumptions: (1) Premenstrual changes should be studied as diversified subtypes rather than as a single premenstrual tension syndrome; such an approach might lead to a better understanding of the pathophysiology of specific types of premenstrual changes. (2) Some specific subtypes of premenstrual changes of a depressive nature resemble some subtypes of affective disorder and, hence, may serve as a model for the study of these disorders.

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