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February 1987

Schizoaffective Psychosis: I. Comparative Long-term Outcome

Author Affiliations

From the Chestnut Lodge Research Institute, Rockville, Md.

Arch Gen Psychiatry. 1987;44(2):130-137. doi:10.1001/archpsyc.1987.01800140032005

• Patients from the Chestnut Lodge (Rockville, Md) followup study with schizoaffective (SA) psychosis (n =68) were compared with patients with DSM-III schizophrenia (S, n =163), bipolar disorder (n =19), and unipolar disorder (n =44) on multiple premorbid, morbid, and outcome dimensions. This study required that patients with SA disorder satisfy DSM-III criteria for both S and affective disorder (minus mutual exclusionary criteria). The SA cohort demographic and premorbid profile paralleled that of the cohort with unipolar disorder. At follow-up, however, the profile of SA psychosis paralleled that of S, with no significant differences between these patients on virtually all outcome measures. Results suggest that among samples of long-term inpatients, SA psychosis as defined herein is closer to S than to affective disorder.

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