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July 1989

Psychobiological Concomitants of History of Suicide Attempts Among Violent Offenders and Impulsive Fire Setters

Author Affiliations

From the Laboratory of Clinical Studies, DICBR, National Institute on Alcohol Abuse and Alcoholism (Drs Virkunnen, De Jong, Bartko, and Linnoila), Division of Biometry and Applied Sciences, Intramural Research Program, National Institute of Mental Health (Dr Bartko), Bethesda, Md; and Department of Psychiatry, University of Helsinki (Finland) (Dr Virkkunen).

Arch Gen Psychiatry. 1989;46(7):604-606. doi:10.1001/archpsyc.1989.01810070030004

• Psychobiological data on 58 violent offenders and impulsive fire setters were analyzed for associations with history of suicide attempts. Subjects with a history of suicide attempts serious enough to require an admission to a medical facility had significantly lower mean cerebrospinal fluid 5-hydroxyindoleacetic acid and 3-methoxy-4-hydroxyphenylglycol concentrations than subjects who had not made such attempts. A linear discriminant function analysis based on psychobiological and behavioral variables correctly classified 79% of the subjects according to the suicide attempt history positive and negative outcomes.