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September 1990

Sleep Architecture in Eating Disorders

Author Affiliations

Department of Psychiatry College of Physicians and Surgeons Columbia University 722 W 168th St New York, NY 10032

Arch Gen Psychiatry. 1990;47(9):880. doi:10.1001/archpsyc.1990.01810210088018

To the Editor.—  In a recent report in the Archives Berger et al1 indicated that there is a contradiction between their findings and an earlier report from our group. In fact, we believe that in all major respects the data by Berger et al are consistent with the conclusions we reached.As noted by Berger et al, their report on the induction of rapid eye movement (REM) sleep by the cholinergic agonist RS-86 contains data relevant not only to depressive illness, but also to eating disorders. In the last several years it has been suggested that patients with anorexia nervosa and bulimia have a predisposition to major depressive illness. In their study, Berger et al found that, compared with controls, 12 patients with eating disorders (6 with anorexia nervosa, 6 with bulimia) did not exhibit the more rapid induction of REM sleep observed in patients with major depressive illness. They

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