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February 1992

Blacks, Schizophrenia, and Neuroleptic Treatment-Reply

Author Affiliations

Department of Psychiatry Medical College of Pennsylvania at Eastern Pennsylvania Psychiatric Institute 3200 Henry Ave Philadelphia, PA 19129

Arch Gen Psychiatry. 1992;49(2):165. doi:10.1001/archpsyc.1992.01820020085014

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In Reply.—  Dr McLeod-Bryant raises interesting and important questions. Of the 53 participants in our study, 26 were white, 26 were black, and one was Oriental (and was omitted from the following analyses). With regard to completers and dropouts, there were fewer dropouts among blacks (nine of 35) than whites (13 of 39); and there were fewer "non-Research Diagnostic Criteria" diagnoses (ie, Research Diagnostic Criteria exclusions for substance abuse or atypical features) among blacks (11 of 33) than whites (23 of 41), a difference that neared significance (×2 = 3.82, P =.051).Blacks and whites did not significantly differ with regard to schizoaffective diagnoses (seven of 26 whites and six of 26 blacks), dystonic reactions, tardive dyskinesia, need for treatmentfor parkinsonian side effects, or achievement of 40% or greater improvement in Brief Psychiatric Rating Scale positive symptoms(hallucinatory behavior + unusual

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