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This Month in Archives of General Psychiatry
February 2003

This Month in Archives of General Psychiatry

Arch Gen Psychiatry. 2003;60(2):119. doi:10.1001/archpsyc.60.2.119

Daumit et al Article studied a national sample of physician visits where antipsychotic medication was prescribed from 1992-2000 in the United States. African American and Hispanic patients had much lower odds of receiving atypical antipsychotics compared with white patients in the early 1990s. As use of atypical antipsychotics became more prevalent throughout the 1990s, these disparities disappeared for Hispanic and improved for African American patients compared with white patients.

Because dehydroepiandrosterone (DHEA) has been shown to improve mood, interest, and activity in a number of studies, Strous et al Article carried out a double-blind, placebo-controlled trial of DHEA in antipsychotic-treated patients with schizophrenia and prominent negative symptoms. Treatment with DHEA was associated with significant improvements in negative symptoms, depression, and anxiety without altering positive symptoms.