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In This Issue of JAMA Psychiatry
April 2017

In This Issue

JAMA Psychiatry. 2017;74(4):309. doi:10.1001/jamapsychiatry.2016.2511

Several psychotherapies were developed specifically for borderline personality disorder. Cristea and colleagues conducted a systematic review and meta-analysis of 33 randomized psychotherapy trials to assess their efficacy. Dialectical behavior therapy and psychodynamic approaches were more effective for outcomes at follow-up. Fonagy and colleagues review the implications for psychotherapy of borderline personality disorder.



Autism spectrum disorder (ASD) is more common in men, but the neurobiological mechanisms for this observation remain elusive. Ecker and colleagues developed a predictive model of biological sex based on cortical thickness in 98 adults with ASD and 98 control individuals and found that probability of ASD increased significantly with male neuroanatomical brain phenotype. These findings suggest normative sex-related phenotypic diversity is related to an individual’s risk of ASD. In an Editorial, Cahill discusses the implications.