Posttraumatic Stress Disorder in Patients After Severe COVID-19 Infection | Infectious Diseases | JAMA Psychiatry | JAMA Network
[Skip to Navigation]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 35.170.64.36. Please contact the publisher to request reinstatement.
1.
Rogers  JP, Chesney  E, Oliver  D,  et al.  Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic.   Lancet Psychiatry. 2020;7(7):611-627. doi:10.1016/S2215-0366(20)30203-0PubMedGoogle ScholarCrossref
2.
Landi  F, Gremese  E, Bernabei  R,  et al; Gemelli Against COVID-19 Post-Acute Care Study Group.  Post-COVID-19 global health strategies: the need for an interdisciplinary approach.   Aging Clin Exp Res. 2020;32(8):1613-1620. doi:10.1007/s40520-020-01616-xPubMedGoogle ScholarCrossref
3.
Galea  S, Brewin  CR, Gruber  M,  et al.  Exposure to hurricane-related stressors and mental illness after Hurricane Katrina.   Arch Gen Psychiatry. 2007;64(12):1427-1434. doi:10.1001/archpsyc.64.12.1427PubMedGoogle ScholarCrossref
4.
Li  X, Aida  J, Hikichi  H, Kondo  K, Kawachi  I.  Association of postdisaster depression and posttraumatic stress disorder with mortality among older disaster survivors of the 2011 Great East Japan Earthquake and Tsunami.   JAMA Netw Open. 2019;2(12):e1917550. doi:10.1001/jamanetworkopen.2019.17550PubMedGoogle Scholar
5.
Galea  S, Ahern  J, Resnick  H,  et al.  Psychological sequelae of the September 11 terrorist attacks in New York City.   N Engl J Med. 2002;346(13):982-987. doi:10.1056/NEJMsa013404PubMedGoogle ScholarCrossref
6.
Carfì  A, Bernabei  R, Landi  F; Gemelli Against COVID-19 Post-Acute Care Study Group.  Persistent symptoms in patients after acute COVID-19.   JAMA. 2020;324(6):603-605. doi:10.1001/jama.2020.12603PubMedGoogle ScholarCrossref
Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words
    1 Comment for this article
    PTSD More Rare than Expected
    Thomas Caffrey, Ph.D. Psychology | Private Practice
    Research indicates repeatedly that chronic PTSD, that is, PTSD that lasts more than 6 months or a year, results in only 10 or 15% of those who sustain Criterion A (the traumatic event). Hence, the high, 30% rate found in the Rome study, as noted in the study, is a finding during the first at most 4 months (120 days); that is, the early phase PTSD, and the phase that typically decreases, by half of more in this instance.
    Thomas Caffrey, Ph.D.
    New York, NY
    CONFLICT OF INTEREST: None Reported
    Research Letter
    February 18, 2021

    Posttraumatic Stress Disorder in Patients After Severe COVID-19 Infection

    Author Affiliations
    • 1Department of Psychiatry, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy
    • 2Department of Geriatrics, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy
    JAMA Psychiatry. 2021;78(5):567-569. doi:10.1001/jamapsychiatry.2021.0109

    Posttraumatic stress disorder (PTSD) may occur in individuals who have experienced a traumatic event. Previous coronavirus epidemics were associated with PTSD diagnoses in postillness stages, with meta-analytic findings indicating a prevalence of 32.2% (95% CI, 23.7-42.0).1 However, information after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is piecemeal. We aimed at filling this gap by studying a group of patients with coronavirus disease 2019 (COVID-19) who sought treatment at the emergency department, most of whom required hospitalization, eventually recovered, and were subsequently referred to a postacute care service for multidisciplinary assessment.

    A total of 381 consecutive patients who presented to the emergency department with SARS-CoV-2 and recovered from COVID-19 infection were referred for a postrecovery health check to a postacute care service established April 21, 2020, at the Fondazione Policlinico Universitario Agostino Gemelli IRCCS in Rome, Italy. Patients were offered a comprehensive and interdisciplinary medical and psychiatric assessment, detailed elsewhere,2 which included data on demographic, clinical, psychopathological, and COVID-19 characteristics. Trained psychiatrists diagnosed PTSD using the criterion-standard Clinician-Administered PTSD Scale for DSM-5 (CAPS-5), reaching a Cohen κ interrater reliability of 0.82. To meet PTSD criteria, in addition to traumatic event exposure (criterion A), patients must have had at least 1 DSM-5 criterion B and C symptom and at least 2 criterion D and E symptoms. Criteria F and G must have been met as well. Additional diagnoses were made through the Structured Clinical Interview for DSM-5. Participants provided written informed consent, and the study was approved by the Università Cattolica and Fondazione Policlinico Gemelli IRCCS Institutional Ethics Committee.

    ×