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In a large population-based study of first-onset psychoses in the United Kingdom, Coid et alArticle demonstrated that the incidence rates of several psychotic syndromes were elevated for both first- and second-generation immigrants, but the exact magnitude of risk was conditional on ethnic group.
In a longitudinal study in monozygotic and dizygotic twin pairs discordant for schizophrenia, Brans et alArticle investigated whether genetic and/or environmental factors are associated with progressive brain volume changes. Both patients with schizophrenia and their unaffected co-twins showed significant decreases over time in whole-brain and frontal and temporal lobe volumes. Moreover, additive genetic influences on schizophrenia liability and progressive brain volume changes were found.
This Month in Archives of General Psychiatry. Arch Gen Psychiatry. 2008;65(11):1243. doi:10.1001/archpsyc.65.11.1243
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