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March 2021 - July 1959

Decade

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Issue

April 2021, Vol 78, No. 4, Pages 348-449

Viewpoint

Psychiatry’s Myopia—Reclaiming the Social, Cultural, and Psychological in the Psychiatric Gaze

Abstract Full Text
JAMA Psychiatry. 2021;78(4):349-350. doi:10.1001/jamapsychiatry.2020.2722

This Viewpoint proposes that psychiatry should more closely attend to the poverty, justice system involvement, and housing issues of people with serious mental illness, supporting this view with quotes from philosophers.

The Rise of Venture Capital Investing in Mental Health

Abstract Full Text
JAMA Psychiatry. 2021;78(4):351-352. doi:10.1001/jamapsychiatry.2020.2847

This Viewpoint discusses potential concerns and benefits related to increasing use of applications for mental health care created by venture capital–backed companies.

COVID-19: Beyond Tomorrow

Targetable Biological Mechanisms Implicated in Emergent Psychiatric Conditions Associated With SARS-CoV-2 Infection

Abstract Full Text
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JAMA Psychiatry. 2021;78(4):353-354. doi:10.1001/jamapsychiatry.2020.2795

This Viewpoint discusses targetable biological mechanisms implicated in emergent psychiatric conditions associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

COVID-19: Beyond Tomorrow

Harnessing Collaborative Care to Meet Mental Health Demands in the Era of COVID-19

Abstract Full Text
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JAMA Psychiatry. 2021;78(4):355-356. doi:10.1001/jamapsychiatry.2020.3216

This Viewpoint discusses the need for collaborative care among health care professionals to meet mental health demands in the COVID-19 pandemic.

COVID-19: Beyond Tomorrow

Opportunities for Research on the Treatment of Substance Use Disorders in the Context of COVID-19

Abstract Full Text
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JAMA Psychiatry. 2021;78(4):357-358. doi:10.1001/jamapsychiatry.2020.3177

This Viewpoint assesses the different ways treatment and research on psychiatric disorders have shifted because of coronavirus disease 2019 (COVID-19) and suggests what changes should remain after the pandemic.

Reducing Common Mental Disorder Prevalence in Populations

Abstract Full Text
JAMA Psychiatry. 2021;78(4):359-360. doi:10.1001/jamapsychiatry.2020.3443

This Viewpoint discusses the need for a paradigm shift in the prevention and evaluation of common mental disorders to lower prevalence on a population basis.

Original Investigation

Internet-Based Cognitive Behavioral Therapy for Depression: A Systematic Review and Individual Patient Data Network Meta-analysis

Abstract Full Text
JAMA Psychiatry. 2021;78(4):361-371. doi:10.1001/jamapsychiatry.2020.4364

This meta-analysis provides personalized estimates of short-term and long-term relative efficacy of guided and unguided internet-based cognitive behavioral therapy for depression using patient-level information.

Trends in US Emergency Department Visits for Mental Health, Overdose, and Violence Outcomes Before and During the COVID-19 Pandemic

Abstract Full Text
free access has active quiz has audio
JAMA Psychiatry. 2021;78(4):372-379. doi:10.1001/jamapsychiatry.2020.4402

This cross-sectional analysis uses data from the Centers for Disease Control and Prevention to examine changes in US emergency department visits for mental health, suicide attempts, overdose, and violence outcomes during the COVID-19 pandemic.

Association of Psychiatric Disorders With Mortality Among Patients With COVID-19

Abstract Full Text
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JAMA Psychiatry. 2021;78(4):380-386. doi:10.1001/jamapsychiatry.2020.4442

This cohort study examines the incidence of mortality in patients with COVID-19 who had premorbid diagnoses of schizophrenia spectrum, mood, or anxiety diagnoses.

Risk of Early-Onset Depression Associated With Polygenic Liability, Parental Psychiatric History, and Socioeconomic Status

Abstract Full Text
JAMA Psychiatry. 2021;78(4):387-397. doi:10.1001/jamapsychiatry.2020.4172

This case-cohort study assesses the individual and joint associations of polygenic risk scores, parental history, and socioeconomic status with relative and absolute risks of early-onset depression.

Identification of Suicide Attempt Risk Factors in a National US Survey Using Machine Learning

Abstract Full Text
JAMA Psychiatry. 2021;78(4):398-406. doi:10.1001/jamapsychiatry.2020.4165

This study evaluates future suicide attempt risk factors in the general population using a data-driven machine learning approach that includes more than 2500 questions from a large, nationally representative survey of US adults.

Association of Heavy Drinking With Deviant Fiber Tract Development in Frontal Brain Systems in Adolescents

Abstract Full Text
JAMA Psychiatry. 2021;78(4):407-415. doi:10.1001/jamapsychiatry.2020.4064

This case-control study uses data from the National Consortium on Alcohol and Neurodevelopment in Adolescence cohort to investigate whether heavy alcohol drinking among adolescents is associated with microstructural brain changes.

Longitudinal Trends in Childhood Insulin Levels and Body Mass Index and Associations With Risks of Psychosis and Depression in Young Adults

Abstract Full Text
open access
JAMA Psychiatry. 2021;78(4):416-425. doi:10.1001/jamapsychiatry.2020.4180

This cohort study examines changes in fasting insulin levels and body mass index from childhood to age 24 years and the risk for psychiatric disorders in that cohort at age 24 years.

Evaluating Depressive Symptoms Among Low-Socioeconomic-Status African American Women Aged 40 to 75 Years With Uncontrolled Hypertension: A Secondary Analysis of a Randomized Clinical Trial

Abstract Full Text
JAMA Psychiatry. 2021;78(4):426-432. doi:10.1001/jamapsychiatry.2020.4622

This secondary analysis of a randomized clinical trial evaluates the prevalence of depressive symptoms among low-socioeconomic-status African American women aged 40 to 75 years with uncontrolled hypertension.

Special Communication

COVID-19: Beyond Tomorrow

Suicide Prevention in the COVID-19 Era: Transforming Threat Into Opportunity

Abstract Full Text
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JAMA Psychiatry. 2021;78(4):433-438. doi:10.1001/jamapsychiatry.2020.3746

This Special Communication discusses what data and recent events during the first 6 months of the coronavirus disease 2019 pandemic reveal about specific effects on suicide risk and outlines actionable steps that policy makers, health care leaders, and organizational leaders can take to mitigate suicide risk during and after the pandemic.

Research Letter

Association of Insulin Resistance With Depression Severity and Remission Status: Defining a Metabolic Endophenotype of Depression

Abstract Full Text
JAMA Psychiatry. 2021;78(4):439-441. doi:10.1001/jamapsychiatry.2020.3669

This study investigates whether insulin resistance was positively associated with the presence, severity, or chronicity of major depression.

Association Between Physical Activity and Schizophrenia: Results of a 2-Sample Mendelian Randomization Analysis

Abstract Full Text
JAMA Psychiatry. 2021;78(4):441-444. doi:10.1001/jamapsychiatry.2020.3946

This mendelian randomization analyzes the potential causality between physical activity and schizophrenia.

Racial Differences in Statewide Suicide Mortality Trends in Maryland During the Coronavirus Disease 2019 (COVID-19) Pandemic

Abstract Full Text
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JAMA Psychiatry. 2021;78(4):444-447. doi:10.1001/jamapsychiatry.2020.3938

This cross-sectional study analyzes trends in suicidality by race/ethnicity during the coronavirus disease 2019 (COVID-19) pandemic.

Comment & Response

Interpreting the Findings of a Meta-analysis of Psychosocial Interventions in Bipolar Disorder

Abstract Full Text
JAMA Psychiatry. 2021;78(4):447-448. doi:10.1001/jamapsychiatry.2020.4412

Interpreting the Findings of a Meta-analysis of Psychosocial Interventions in Bipolar Disorder

Abstract Full Text
JAMA Psychiatry. 2021;78(4):448. doi:10.1001/jamapsychiatry.2020.4418

Interpreting the Findings of a Meta-analysis of Psychosocial Interventions in Bipolar Disorder

Abstract Full Text
JAMA Psychiatry. 2021;78(4):448-449. doi:10.1001/jamapsychiatry.2020.4424
Correction

Error in Results, Figures, and Tables

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(4):449. doi:10.1001/jamapsychiatry.2021.0127
JAMA Psychiatry Masthead

JAMA Psychiatry

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(4):348. doi:10.1001/jamapsychiatry.2020.3122
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