April 2021, Vol 78, No. 4, Pages 348-449

This meta-analysis provides personalized estimates of short-term and long-term relative efficacy of guided and unguided internet-based cognitive behavioral therapy for depression using patient-level information.

This cross-sectional analysis uses data from the Centers for Disease Control and Prevention to examine changes in US emergency department visits for mental health, suicide attempts, overdose, and violence outcomes during the COVID-19 pandemic.

This cohort study examines the incidence of mortality in patients with COVID-19 who had premorbid diagnoses of schizophrenia spectrum, mood, or anxiety diagnoses.

This case-cohort study assesses the individual and joint associations of polygenic risk scores, parental history, and socioeconomic status with relative and absolute risks of early-onset depression.

This study evaluates future suicide attempt risk factors in the general population using a data-driven machine learning approach that includes more than 2500 questions from a large, nationally representative survey of US adults.

This case-control study uses data from the National Consortium on Alcohol and Neurodevelopment in Adolescence cohort to investigate whether heavy alcohol drinking among adolescents is associated with microstructural brain changes.

This cohort study examines changes in fasting insulin levels and body mass index from childhood to age 24 years and the risk for psychiatric disorders in that cohort at age 24 years.

This secondary analysis of a randomized clinical trial evaluates the prevalence of depressive symptoms among low-socioeconomic-status African American women aged 40 to 75 years with uncontrolled hypertension.