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October 2018 - July 1959

Decade

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Issue

December 2014, Vol 71, No. 12, Pages 1311-1421

In This Issue of JAMA Psychiatry

Highlights

Abstract Full Text
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JAMA Psychiatry. 2014;71(12):1311. doi:10.1001/jamapsychiatry.2013.2769
Viewpoint

A Breakthrough in Schizophrenia Genetics

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JAMA Psychiatry. 2014;71(12):1319-1320. doi:10.1001/jamapsychiatry.2014.1776

This Viewpoint discusses lessons learned from a recent article from the Schizophrenia Working Group of the Psychiatric Genomics Consortium on 108 schizophrenia-associated genetic loci.

Art and Images in Psychiatry

Cunningham Dax Collection

Abstract Full Text
JAMA Psychiatry. 2014;71(12):1316-1317. doi:10.1001/jamapsychiatry.2013.2771
Editorial

Farewell

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JAMA Psychiatry. 2014;71(12):1321-1322. doi:10.1001/jamapsychiatry.2014.2282
Original Investigation

Prefrontal Cortical Dendritic Spine Pathology in Schizophrenia and Bipolar Disorder

Abstract Full Text
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JAMA Psychiatry. 2014;71(12):1323-1331. doi:10.1001/jamapsychiatry.2014.1582

This study assesses dendritic spine loss in the dorsolateral prefrontal cortex in individuals with schizophrenia and individuals with bipolar disorder and suggests that the 2 disorders may share some common pathophysiological features.

Treating Prolonged Grief DisorderA Randomized Clinical Trial

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JAMA Psychiatry. 2014;71(12):1332-1339. doi:10.1001/jamapsychiatry.2014.1600

This randomized clinical trial shows that cognitive behavior therapy that includes exposure therapy to treat prolonged grief disorder facilitates emotional responses that reduce symptoms.

The Norepinephrine Transporter in Attention-Deficit/Hyperactivity Disorder Investigated With Positron Emission Tomography

Abstract Full Text
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JAMA Psychiatry. 2014;71(12):1340-1349. doi:10.1001/jamapsychiatry.2014.1226

This prospective study does not identify any involvement of changes in brain norepinephrine transporter availability or distribution in the pathogenesis of attention-deficit/hyperactivity disorder.

Cardiometabolic Risk in Patients With First-Episode Schizophrenia Spectrum DisordersBaseline Results From the RAISE-ETP Study

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JAMA Psychiatry. 2014;71(12):1350-1363. doi:10.1001/jamapsychiatry.2014.1314

This study assesses cardiometabolic risk in patients with first-episode schizophrenia spectrum disorders.

Increased Release of Dopamine in the Striata of Young Adults With Hearing Impairment and Its Relevance for the Social Defeat Hypothesis of Schizophrenia

Abstract Full Text
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JAMA Psychiatry. 2014;71(12):1364-1372. doi:10.1001/jamapsychiatry.2014.1325

This study presents preliminary evidence of dopamine sensitization in a socially excluded group of people with hearing impairment.

Depressive Symptoms and Physical Activity During 3 Decades in Adult LifeBidirectional Associations in a Prospective Cohort Study

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JAMA Psychiatry. 2014;71(12):1373-1380. doi:10.1001/jamapsychiatry.2014.1240

This prospective cohort study suggests that activity may alleviate depressive symptoms in the general population, whereas depressive symptoms in early adulthood may be a barrier to physical activity.

Meta-analysis

Effect of Anti-inflammatory Treatment on Depression, Depressive Symptoms, and Adverse EffectsA Systematic Review and Meta-analysis of Randomized Clinical Trials

Abstract Full Text
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JAMA Psychiatry. 2014;71(12):1381-1391. doi:10.1001/jamapsychiatry.2014.1611

This meta-analysis supports a proof-of-concept concerning use of anti-inflammatory treatment in depression.

Correcting Systematic Inflation in Genetic Association Tests That Consider Interaction EffectsApplication to a Genome-wide Association Study of Posttraumatic Stress Disorder

Abstract Full Text
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JAMA Psychiatry. 2014;71(12):1392-1399. doi:10.1001/jamapsychiatry.2014.1339

This study concludes that the robust joint test be used in candidate-gene and genome-wide association studies of psychiatric outcomes that consider environmental interactions.

Associations Between Subjective Social Status and DSM-IV Mental DisordersResults From the World Mental Health Surveys

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JAMA Psychiatry. 2014;71(12):1400-1408. doi:10.1001/jamapsychiatry.2014.1337

This cross-sectional study conducted in 18 countries reports significant inverse associations between subjective social status and numerous DSM-IV mental disorders.

Meta-analysis

Placebo Response in Antipsychotic Clinical TrialsA Meta-analysis

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JAMA Psychiatry. 2014;71(12):1409-1421. doi:10.1001/jamapsychiatry.2014.1319

This meta-analysis reports that the average treatment change associated with placebo treatment in antipsychotic trials increased since 1960, while the change associated with medication treatment decreased.

Correction

Addition to Author Contributions

Abstract Full Text
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JAMA Psychiatry. 2014;71(12):1408. doi:10.1001/jamapsychiatry.2014.2512

Error in Byline

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JAMA Psychiatry. 2014;71(12):1408. doi:10.1001/jamapsychiatry.2014.2573
JAMA Psychiatry Masthead

JAMA Psychiatry

Abstract Full Text
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JAMA Psychiatry. 2014;71(12):1314. doi:10.1001/jamapsychiatry.2013.2770
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