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May 2019 - July 1959

Decade

Year

Issue

April 2015, Vol 72, No. 4, Pages 301-399

In This Issue of JAMA Psychiatry

Highlights

Abstract Full Text
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JAMA Psychiatry. 2015;72(4):301. doi:10.1001/jamapsychiatry.2014.1876
Viewpoint

Assessing and Improving Clinical Insight Among Patients “in Denial”

Abstract Full Text
JAMA Psychiatry. 2015;72(4):303-304. doi:10.1001/jamapsychiatry.2014.2684

This Viewpoint discusses the differences between patients experiencing denial and those exhibiting lack of insight and addresses interventions that may improve care for patients exhibiting lack of insight.

Original Investigation

Meta-analysis

Identification of a Common Neurobiological Substrate for Mental Illness

Abstract Full Text
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JAMA Psychiatry. 2015;72(4):305-315. doi:10.1001/jamapsychiatry.2014.2206

This meta-analysis identified a concordance across psychiatric diagnoses in terms of integrity of an anterior insula/dorsal anterior cingulate–based network, which may relate to executive function deficits observed across diagnoses.

Deficits in Prefrontal Cortical and Extrastriatal Dopamine Release in Schizophrenia: A Positron Emission Tomographic Functional Magnetic Resonance Imaging Study

Abstract Full Text
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JAMA Psychiatry. 2015;72(4):316-324. doi:10.1001/jamapsychiatry.2014.2414

This positron emission tomographic functional magnetic resonance imaging study found in vivo evidence for a deficit in the capacity for dopamine release in the dorsolateral prefrontal cortex in schizophrenia.

Lifetime Prevalence, Age of Risk, and Genetic Relationships of Comorbid Psychiatric Disorders in Tourette Syndrome

Abstract Full Text
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JAMA Psychiatry. 2015;72(4):325-333. doi:10.1001/jamapsychiatry.2014.2650

This cross-sectional study demonstrates that psychiatric comorbidities are common among individuals with Tourette syndrome and that most comorbidities begin early in life.

Meta-analysis

Mortality in Mental Disorders and Global Disease Burden Implications: A Systematic Review and Meta-analysis

Abstract Full Text
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JAMA Psychiatry. 2015;72(4):334-341. doi:10.1001/jamapsychiatry.2014.2502

This meta-analysis suggests that mental disorders rank among the most important causes of death worldwide.

Associations Between Obsessive-Compulsive Classes and Pathological Gambling in a National Cohort of Male Twins

Abstract Full Text
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JAMA Psychiatry. 2015;72(4):342-349. doi:10.1001/jamapsychiatry.2014.2497

This latent class analysis of obsessive-compulsive (OC) features, cross-sectional tests of association, and classic twin genetic analysis finds phenotypic and genetic overlap between OC and pathological gambling.

Disrupted Effective Connectivity of Cortical Systems Supporting Attention and Interoception in Melancholia

Abstract Full Text
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JAMA Psychiatry. 2015;72(4):350-358. doi:10.1001/jamapsychiatry.2014.2490

This observational study finds reduced effective connectivity in resting-state functional magnetic resonance imaging between key networks involved in attention and interoception in melancholia.

Familial Clustering of Tic Disorders and Obsessive-Compulsive Disorder

Abstract Full Text
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JAMA Psychiatry. 2015;72(4):359-366. doi:10.1001/jamapsychiatry.2014.2656

This population-based study of national health registries in Denmark finds that Tourette syndrome/chronic tic disorder (TS/CT) and obsessive-compulsive disorder (OCD) cluster in families, with a higher familial aggregation for TS/CT.

White Matter Structure in Youth With Behavioral and Emotional Dysregulation Disorders: A Probabilistic Tractographic Study

Abstract Full Text
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JAMA Psychiatry. 2015;72(4):367-376. doi:10.1001/jamapsychiatry.2014.2170

This neuroimaging study suggests that abnormal uncinate fasciculus and cingulum white matter structure may underlie emotional, but not behavioral, dysregulation in pediatric psychiatric disorders.

Cognitive Decline Preceding the Onset of Psychosis in Patients With 22q11.2 Deletion Syndrome

Abstract Full Text
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JAMA Psychiatry. 2015;72(4):377-385. doi:10.1001/jamapsychiatry.2014.2671

This prospective longitudinal cohort study determines whether early cognitive decline is associated with risk of psychotic disorder in patients with 22q11.2 deletion syndrome.

Prediction of Autism by Translation and Immune/Inflammation Coexpressed Genes in Toddlers From Pediatric Community Practices

Abstract Full Text
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JAMA Psychiatry. 2015;72(4):386-394. doi:10.1001/jamapsychiatry.2014.3008

This proof-of-principle study demonstrated that genomic biomarkers with very good sensitivity and specificity for boys with autism spectrum disorder in general pediatric settings can be identified.

Research Letter

The Untapped Potential of Office-Based Buprenorphine Treatment

Abstract Full Text
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JAMA Psychiatry. 2015;72(4):395-396. doi:10.1001/jamapsychiatry.2014.2421

Amygdala-Hippocampal Volume and the Phenotypic Heterogeneity of Posttraumatic Stress Disorder: A Cross-Sectional Study

Abstract Full Text
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JAMA Psychiatry. 2015;72(4):396-398. doi:10.1001/jamapsychiatry.2014.2470
Comment & Response

Childhood Trauma–Specific Reductions in Limbic Gray Matter Volume: Still in the Dark

Abstract Full Text
JAMA Psychiatry. 2015;72(4):398. doi:10.1001/jamapsychiatry.2014.2680

Childhood Trauma–Specific Reductions in Limbic Gray Matter Volume—Reply

Abstract Full Text
JAMA Psychiatry. 2015;72(4):398-399. doi:10.1001/jamapsychiatry.2014.2682
Peer Reviewers List

JAMA Psychiatry Peer Reviewers in 2014

Abstract Full Text
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JAMA Psychiatry. 2015;72(4):e150294. doi:10.1001/jamapsychiatry.2015.0294
JAMA Psychiatry Masthead

JAMA Psychiatry

Abstract Full Text
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JAMA Psychiatry. 2015;72(4):302. doi:10.1001/jamapsychiatry.2014.1877
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