This Viewpoint discusses true evidence-based practice and using it to personalize treatment for military veterans and servicemembers with posttraumatic stress disorder.
This Viewpoint suggests that the assertion that prolonged exposure or cognitive processing therapy should be the dominant evidence-based treatments for war-related PTSD is simplistic and may at times be unhelpful or contraindicated.
This Viewpoint reports that the direction of suicide prevention research must change if more lives are to be saved.
The SALOME randomized clinical trial tests if injectable hydromorphone is noninferior to injectable diacetylmorphine in reducing illicit heroin use after 6 months of intervention.
This randomized clinical trial evaluates the effects of deep brain stimulation in patients with treatment-resistant depression and, in a crossover design, compares active and sham phases for possible detection of placebo effects.
This cohort study determines whether the developmental processes that predispose to schizophrenia are better reflected by the observed cognitive performance in adolescence or the deviation of that performance from an individual’s familial cognitive aptitude.
This genome-wide association study assesses analyses from 3 studies of substance use disorder genetics to identify DSM-IV criteria for cannabis dependence in a large African American and European American cohort.
This study uses data from the Philadelphia Neurodevelopmental Cohort to evaluate the charting of brain intrinsic connectivity network patterns to serve as a measure of attention functioning in youth.
This randomized clinical trial evaluates the use of N-acetylcysteine in short-term treatment of skin-picking disorder.
This investigation uses multiple independent genome-wide association study data sets to determine if there is a genetic association between schizophrenia and age at first birth using genetically informative but independently ascertained data sets.
This epigenome-wide association study examines differentially methylated positions across the genome in blood-derived DNA samples in a discovery and a replication set.
Using a subsample of individuals from the Philadelphia Neurodevelopmental Cohort, this study investigates the presence of structural brain abnormalities in youth with psychosis spectrum symptoms.
This prospective cohort study of black and white community-dwelling older adults in the Health, Aging, and Body Composition study investigates the association between trajectories of depressive symptoms and risk of dementia in older adults.