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September 2019 - July 1959

Decade

Year

Issue

December 2017, Vol 74, No. 12, Pages 1181-1279

In This Issue of JAMA Psychiatry

Highlights

Abstract Full Text
free access
JAMA Psychiatry. 2017;74(12):1181. doi:10.1001/jamapsychiatry.2016.2551
Viewpoint

Bigger Data, Harder Questions—Opportunities Throughout Mental Health Care

Abstract Full Text
JAMA Psychiatry. 2017;74(12):1183-1184. doi:10.1001/jamapsychiatry.2017.3333

This Viewpoint describes the benefits and potential pitfalls of using “big data” to answer hard questions about the practice of clinical psychiatry.

Editorial

Evidence-Based Pragmatic Psychiatry—A Call to Action

Abstract Full Text
JAMA Psychiatry. 2017;74(12):1185-1186. doi:10.1001/jamapsychiatry.2017.2439

Dopamine Dysfunction in Schizophrenia and Bipolar Disorder—Never the Twain Shall Meet?

Abstract Full Text
JAMA Psychiatry. 2017;74(12):1187-1188. doi:10.1001/jamapsychiatry.2017.2330

Leveraging Molecular Genetic Approaches to Yield Insights Into Major Depression Etiology and Clinical Presentation

Abstract Full Text
JAMA Psychiatry. 2017;74(12):1189-1190. doi:10.1001/jamapsychiatry.2017.3017

Inference in Psychiatry via 2-Sample Mendelian Randomization—From Association to Causal Pathway?

Abstract Full Text
JAMA Psychiatry. 2017;74(12):1191-1192. doi:10.1001/jamapsychiatry.2017.3162

Challenges in the Study of Genetic Variants of Comorbid Alcohol Use Disorder and Major Depression

Abstract Full Text
JAMA Psychiatry. 2017;74(12):1193-1194. doi:10.1001/jamapsychiatry.2017.3353

Death by Gun Violence—A Public Health Crisis

Abstract Full Text
free access
JAMA Psychiatry. 2017;74(12):1195-1196. doi:10.1001/jamapsychiatry.2017.3616
Original Investigation

Effectiveness of Injectable Extended-Release Naltrexone vs Daily Buprenorphine-Naloxone for Opioid Dependence: A Randomized Clinical Noninferiority Trial

Abstract Full Text
free access has active quiz
JAMA Psychiatry. 2017;74(12):1197-1205. doi:10.1001/jamapsychiatry.2017.3206

This randomized clinical trial compares the effectiveness of extended-release naltrexone with that of buprenorphine-naloxone in maintaining short-term abstinence from heroin and other illicit substances.

A Test of the Transdiagnostic Dopamine Hypothesis of Psychosis Using Positron Emission Tomographic Imaging in Bipolar Affective Disorder and Schizophrenia

Abstract Full Text
open access
JAMA Psychiatry. 2017;74(12):1206-1213. doi:10.1001/jamapsychiatry.2017.2943

This cross-sectional case-control positron emission tomographic study tests whether dopamine synthesis capacity is elevated in bipolar disorder with psychosis and how this compares with schizophrenia and matched controls.

Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations

Abstract Full Text
free access
JAMA Psychiatry. 2017;74(12):1214-1225. doi:10.1001/jamapsychiatry.2017.3016

This consortium study of multiple data sets assesses whether patients with major depressive disorder had different degrees of genetic overlap with obesity-related traits.

Inflammatory Biomarkers and Risk of Schizophrenia: A 2-Sample Mendelian Randomization Study

Abstract Full Text
open access
JAMA Psychiatry. 2017;74(12):1226-1233. doi:10.1001/jamapsychiatry.2017.3191

This study uses mendelian randomization of candidate gene or genome-wide association studies to evaluate the association between inflammatory biomarkers and the risk of schizophrenia.

Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression

Abstract Full Text
free access
JAMA Psychiatry. 2017;74(12):1234-1241. doi:10.1001/jamapsychiatry.2017.3275

This genome-wide association study uses data from the Yale-Penn study to detect genetic risk variants for comorbid alcohol dependence and major depression and to determine whether polygenic risk alleles are shared with neuropsychiatric traits or subcortical brain volumes.

Genome-Wide Association Studies of a Broad Spectrum of Antisocial Behavior

Abstract Full Text
free access
JAMA Psychiatry. 2017;74(12):1242-1250. doi:10.1001/jamapsychiatry.2017.3069

This study estimates the single-nucleotide polymorphism–based heritability of antisocial behavior; identifies novel genetic risk variants, genes, or biological pathways; tests for pleiotropic effects with other psychiatric traits; and reevaluates the candidate gene era data through the Broad Antisocial Behavior Consortium.

Comparison of Simulated Treatment and Cost-effectiveness of a Stepped Care Case-Finding Intervention vs Usual Care for Posttraumatic Stress Disorder After a Natural Disaster

Abstract Full Text
free access
JAMA Psychiatry. 2017;74(12):1251-1258. doi:10.1001/jamapsychiatry.2017.3037

This simulation study compares a stepped care case-finding intervention vs a moderate-strength single-level intervention on treatment effectiveness and cost-effectiveness in the 2 years after a natural disaster.

Personality Change in the Preclinical Phase of Alzheimer Disease

Abstract Full Text
free access
JAMA Psychiatry. 2017;74(12):1259-1265. doi:10.1001/jamapsychiatry.2017.2816

This cohort study examines whether changes in personality traits develop before the onset of mild cognitive impairment or dementia in individuals with no initial impairment.

Extent of Dorsolateral Prefrontal Cortex Plasticity and Its Association With Working Memory in Patients With Alzheimer Disease

Abstract Full Text
free access
JAMA Psychiatry. 2017;74(12):1266-1274. doi:10.1001/jamapsychiatry.2017.3292

This cross-sectional study assesses the dorsolateral prefrontal cortex plasticity and its association with working memory in patients with early Alzheimer disease.

Neuroscience and Psychiatry

Mood Instability and Reward Dysregulation—A Neurocomputational Model of Bipolar Disorder

Abstract Full Text
JAMA Psychiatry. 2017;74(12):1275-1276. doi:10.1001/jamapsychiatry.2017.3163

This Viewpoint discusses a neurocomputational model of bipolar disorder and makes predictions about how mood changes will escalate, resolve, and reverse in bipolar disorder.

Comment & Response

Deviations From Clinical Trials Registration in the ED-SAFE Study—Reply

Abstract Full Text
JAMA Psychiatry. 2017;74(12):1278-1279. doi:10.1001/jamapsychiatry.2017.2487

Deviations From Clinical Trials Registration in the ED-SAFE Study

Abstract Full Text
JAMA Psychiatry. 2017;74(12):1278. doi:10.1001/jamapsychiatry.2017.3080
Correction

Missing Degree in Author Byline

Abstract Full Text
free access
JAMA Psychiatry. 2017;74(12):1279. doi:10.1001/jamapsychiatry.2017.3229

Error in Results

Abstract Full Text
free access
JAMA Psychiatry. 2017;74(12):1279. doi:10.1001/jamapsychiatry.2017.3375

Errors in Byline and Table 1 Footnote

Abstract Full Text
free access
JAMA Psychiatry. 2017;74(12):1279. doi:10.1001/jamapsychiatry.2017.3848
JAMA Psychiatry Masthead

JAMA Psychiatry

Abstract Full Text
free access
JAMA Psychiatry. 2017;74(12):1182. doi:10.1001/jamapsychiatry.2016.2552
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