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October 2019 - July 1959

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Issue

October 2019, Vol 76, No. 10, Pages 997-1098

In This Issue of JAMA Psychiatry

Highlights

Abstract Full Text
free access
JAMA Psychiatry. 2019;76(10):997. doi:10.1001/jamapsychiatry.2018.3005
Viewpoint

Leveraging Digital Health and Machine Learning Toward Reducing Suicide—From Panacea to Practical Tool

Abstract Full Text
JAMA Psychiatry. 2019;76(10):999-1000. doi:10.1001/jamapsychiatry.2019.1231

This Viewpoint describes technological improvements that could be used to augment clinical care for individuals at risk of suicide, thus reducing suicide attempts and deaths.

The First Food and Drug Administration–Indicated Drug for Postpartum Depression—Brexanolone

Abstract Full Text
JAMA Psychiatry. 2019;76(10):1001-1002. doi:10.1001/jamapsychiatry.2019.1546

This Viewpoint discusses randomized clinical trials that have tested a new drug, brexanolone, to treat women with postpartum depression.

Editorial

A Unique Genome-wide Association Study of a Psychiatric Disorder From India

Abstract Full Text
JAMA Psychiatry. 2019;76(10):1003-1004. doi:10.1001/jamapsychiatry.2019.1325

The Architecture of Autism Spectrum Disorder Risk: What Do We Know, and Where Do We Go From Here?

Abstract Full Text
JAMA Psychiatry. 2019;76(10):1005-1006. doi:10.1001/jamapsychiatry.2019.1375

Clozapine and Evidence-Based Psychopharmacology for Schizophrenia

Abstract Full Text
JAMA Psychiatry. 2019;76(10):1007-1008. doi:10.1001/jamapsychiatry.2019.1656
Original Investigation

Effect of Adjunctive Estradiol on Schizophrenia Among Women of Childbearing Age: A Randomized Clinical Trial

Abstract Full Text
has active quiz
JAMA Psychiatry. 2019;76(10):1009-1017. doi:10.1001/jamapsychiatry.2019.1842

This randomized clinical trial examines the effect of transdermal estradiol added to antipsychotic treatment in women of childbearing age with schizophrenia.

Efficacy of Short-term Treatment of Internet and Computer Game Addiction: A Randomized Clinical Trial

Abstract Full Text
has audio
JAMA Psychiatry. 2019;76(10):1018-1025. doi:10.1001/jamapsychiatry.2019.1676

This randomized clinical trial evaluates the efficacy of manualized cognitive behavioral therapy in men with internet and computer game addiction.

Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study

Abstract Full Text
JAMA Psychiatry. 2019;76(10):1026-1034. doi:10.1001/jamapsychiatry.2019.1335

This genome-wide association study evaluates genetic loci for schizophrenia in a unique Indian population.

Association of Genetic and Environmental Factors With Autism in a 5-Country Cohort

Abstract Full Text
JAMA Psychiatry. 2019;76(10):1035-1043. doi:10.1001/jamapsychiatry.2019.1411

This population-based cohort study uses national registry data from 5 countries to investigate additive genetic, maternal, and environmental effects on autism spectrum disorder diagnosis.

Association Between Childhood Behaviors and Adult Employment Earnings in Canada

Abstract Full Text
has audio
JAMA Psychiatry. 2019;76(10):1044-1051. doi:10.1001/jamapsychiatry.2019.1326

This study analyzes 30 years of data from the Quebec Longitudinal Study of Kindergarten Children to identify elementary school–aged behaviors that may increase the likelihood of future socioeconomic disadvantages.

Association With Hospitalization and All-Cause Discontinuation Among Patients With Schizophrenia on Clozapine vs Other Oral Second-Generation Antipsychotics: A Systematic Review and Meta-analysis of Cohort Studies

Abstract Full Text
JAMA Psychiatry. 2019;76(10):1052-1062. doi:10.1001/jamapsychiatry.2019.1702

This systematic review and meta-analysis compares various outcomes of clozapine vs oral nonclozapine second-generation antipsychotics in cohort studies of patients with schizophrenia.

Evaluation of Differences in Individual Treatment Response in Schizophrenia Spectrum Disorders: A Meta-analysis

Abstract Full Text
JAMA Psychiatry. 2019;76(10):1063-1073. doi:10.1001/jamapsychiatry.2019.1530

This meta-analysis assesses individualized response to treatment and reviews treatment-by-patient interaction among patients with schizophrenia.

In Vivo Availability of Cannabinoid 1 Receptor Levels in Patients With First-Episode Psychosis

Abstract Full Text
open access
JAMA Psychiatry. 2019;76(10):1074-1084. doi:10.1001/jamapsychiatry.2019.1427

This cross-sectional case-control cohort study investigates availability of cannabinoid 1 receptor in patients with first-episode psychosis without the confounds of substance use, antipsychotic medication use, or illness chronicity.

Editor's Note

Challenges When Conducting Complex Clinical Research

Abstract Full Text
JAMA Psychiatry. 2019;76(10):1017. doi:10.1001/jamapsychiatry.2019.1657
Special Communication

From Many to One to Many—the Search for Causes of Psychiatric Illness

Abstract Full Text
JAMA Psychiatry. 2019;76(10):1085-1091. doi:10.1001/jamapsychiatry.2019.1200

This Special Communication describes the history of the psychiatric field to discover a single cause or many causes of specific psychiatric disorders and discusses whether doing so will legitimate the discipline of psychiatry.

JAMA Network Insights

What to Tell a Parent Who Worries a Young Child Has Autism

Abstract Full Text
JAMA Psychiatry. 2019;76(10):1092-1093. doi:10.1001/jamapsychiatry.2019.1234

This article summarizes evidence for diagnosis of autism spectrum disorder in young children.

Research Letter

Association of Quetiapine Overuse Letters With Prescribing by Physician Peers of Targeted Recipients: A Secondary Analysis of a Randomized Clinical Trial

Abstract Full Text
JAMA Psychiatry. 2019;76(10):1094-1095. doi:10.1001/jamapsychiatry.2019.1418

This secondary analysis of a randomized clinical trial examines the association of antipsychotic overuse letters with changes in the prescription of quetiapine by physician peers.

Comment & Response

Lead Exposure as a Confounding Factor in the Association of Air Pollution Exposure and Psychotic Experiences

Abstract Full Text
JAMA Psychiatry. 2019;76(10):1095-1096. doi:10.1001/jamapsychiatry.2019.1691

Lead Exposure as a Confounding Factor in the Association of Air Pollution Exposure and Psychotic Experiences—Reply

Abstract Full Text
JAMA Psychiatry. 2019;76(10):1096-1097. doi:10.1001/jamapsychiatry.2019.1699

Posttraumatic Stress Disorder and Cognitive Processing Therapy in Youth

Abstract Full Text
JAMA Psychiatry. 2019;76(10):1097. doi:10.1001/jamapsychiatry.2019.1968

Posttraumatic Stress Disorder and Cognitive Processing Therapy in Youth–Reply

Abstract Full Text
JAMA Psychiatry. 2019;76(10):1097-1098. doi:10.1001/jamapsychiatry.2019.1971
Correction

Numeric Errors in Table 2

Abstract Full Text
free access
JAMA Psychiatry. 2019;76(10):1098. doi:10.1001/jamapsychiatry.2019.2685
JAMA Psychiatry Masthead

JAMA Psychiatry

Abstract Full Text
free access
JAMA Psychiatry. 2019;76(10):998. doi:10.1001/jamapsychiatry.2018.3006
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