[Skip to Navigation]
Sign In

August 2021 - July 1959




February 2021, Vol 78, No. 2, Pages 119-224


The Current Status of Psychedelics in Psychiatry

Abstract Full Text
JAMA Psychiatry. 2021;78(2):121-122. doi:10.1001/jamapsychiatry.2020.2171

This Viewpoint describes current regulations and research on psychedelic use in psychiatry.

COVID-19: Beyond Tomorrow

Meeting Maternal Mental Health Needs During the COVID-19 Pandemic

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(2):123-124. doi:10.1001/jamapsychiatry.2020.1947

This Viewpoint discusses current mental health concerns for pregnant and postpartum women in light of the coronavirus disease 2019 pandemic.

Tapering Antipsychotic Treatment

Abstract Full Text
JAMA Psychiatry. 2021;78(2):125-126. doi:10.1001/jamapsychiatry.2020.2166

This Viewpoint discusses principles for tapering antipsychotic treatment when deprescribing them.

Prediction, Not Association, Paves the Road to Precision Medicine

Abstract Full Text
JAMA Psychiatry. 2021;78(2):127-128. doi:10.1001/jamapsychiatry.2020.2549

This Viewpoint articulates the distinction between association and prediction in psychiatric research studies.

Now Is the Time to Support Black Individuals in the US Living With Serious Mental Illness—A Call to Action

Abstract Full Text
JAMA Psychiatry. 2021;78(2):129-130. doi:10.1001/jamapsychiatry.2020.2656

This Viewpoint discusses how mental health researchers and clinicians can support Black individuals in the US, especially those with serious mental illness.


Beyond Efficacy and Toward Dissemination and Personalization of Psychotherapy for Bipolar Disorder

Abstract Full Text
JAMA Psychiatry. 2021;78(2):131-132. doi:10.1001/jamapsychiatry.2020.2980
Original Investigation

Effect of Cognitive Bias Modification on Early Relapse Among Adults Undergoing Inpatient Alcohol Withdrawal Treatment: A Randomized Clinical Trial

Abstract Full Text
has active quiz
JAMA Psychiatry. 2021;78(2):133-140. doi:10.1001/jamapsychiatry.2020.3446

This randomized clinical trial assesses whether cognitive bias modification would increase the likelihood of abstaining from alcohol during the 2 weeks following discharge from inpatient withdrawal treatment in adult patients with alcohol use disorder.

Adjunctive Psychotherapy for Bipolar Disorder: A Systematic Review and Component Network Meta-analysis

Abstract Full Text
JAMA Psychiatry. 2021;78(2):141-150. doi:10.1001/jamapsychiatry.2020.2993

This systematic review and component network meta-analysis compares the association of manualized psychotherapies and therapy components with the reduction of recurrences and stabilizing symptoms in patients with bipolar disorder.

Prescription Opioid Use and Risk for Major Depressive Disorder and Anxiety and Stress-Related Disorders: A Multivariable Mendelian Randomization Analysis

Abstract Full Text
open access
JAMA Psychiatry. 2021;78(2):151-160. doi:10.1001/jamapsychiatry.2020.3554

This mendelian randomization analysis investigates the potential bidirectional associations between the genetic liability for prescription opioid and other nonopioid pain medications and both major depressive disorder and anxiety and stress-related disorders using genetically based methods

Dissecting the Association Between Inflammation, Metabolic Dysregulation, and Specific Depressive Symptoms: A Genetic Correlation and 2-Sample Mendelian Randomization Study

Abstract Full Text
open access
JAMA Psychiatry. 2021;78(2):161-170. doi:10.1001/jamapsychiatry.2020.3436

This genetic correlation and 2-sample mendelian randomization study uses large-scale genome-wide association data sources to explore the genetic overlap and associations between inflammatory activity, metabolic dysregulation, and individual depressive symptoms.

Trends in Suicidality 1 Year Before and After Birth Among Commercially Insured Childbearing Individuals in the United States, 2006-2017

Abstract Full Text
JAMA Psychiatry. 2021;78(2):171-176. doi:10.1001/jamapsychiatry.2020.3550

This cross-sectional study evaluates prevalence and trends in suicidality (suicidal ideation and/or intentional self-harm) among commercially insured childbearing individuals 1 year before and following birth.

Assessment of the Risk of Psychiatric Disorders, Use of Psychiatric Hospitals, and Receipt of Psychiatric Medication Among Patients With Lyme Neuroborreliosis in Denmark

Abstract Full Text
JAMA Psychiatry. 2021;78(2):177-186. doi:10.1001/jamapsychiatry.2020.2915

This cohort study uses data from Danish national registries to examine the risk of psychiatric disease, the percentage of psychiatric hospital inpatient and outpatient contacts, and the receipt of prescribed psychiatric medications among patients with Lyme neuroborreliosis in Denmark.

Association of Borderline Personality Disorder Criteria With Suicide Attempts: Findings From the Collaborative Longitudinal Study of Personality Disorders Over 10 Years of Follow-up

Abstract Full Text
JAMA Psychiatry. 2021;78(2):187-194. doi:10.1001/jamapsychiatry.2020.3598

This study examines prospective factors associated with suicide attempts among participants over 10 years of follow-up, with a focus on borderline personality disorder and its diagnostic criteria.

Multimodal Machine Learning Workflows for Prediction of Psychosis in Patients With Clinical High-Risk Syndromes and Recent-Onset Depression

Abstract Full Text
open access
JAMA Psychiatry. 2021;78(2):195-209. doi:10.1001/jamapsychiatry.2020.3604

This prognostic study evaluates whether psychosis transition can be predicted in patients with clinical high-risk syndromes or recent-onset depression by multimodal machine learning that optimally integrates clinical and neurocognitive data, structural magnetic resonance imaging, and polygenic risk scores for schizophrenia.


Could Polygenic Risk Scores Be Useful in Psychiatry?A Review

Abstract Full Text
JAMA Psychiatry. 2021;78(2):210-219. doi:10.1001/jamapsychiatry.2020.3042

This narrative review describes current and potential future use of polygenic risk scores in psychiatric clinical practice, with a focus on diagnosis, treatment, and prognosis in schizophrenia and depression.

JAMA Network Insights

Five Things to Know When a Psychiatric Patient Is Prescribed Opioids for Pain

Abstract Full Text
JAMA Psychiatry. 2021;78(2):220-221. doi:10.1001/jamapsychiatry.2020.3547

This essay describes how psychiatrists can play an important role in optimizing care for patients who have been prescribed opioids for chronic pain.

Research Letter

Effect of Escalating and Deescalating Financial Incentives vs Usual Care to Improve Antidepressant Adherence: A Pilot Randomized Clinical Trial

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(2):222-224. doi:10.1001/jamapsychiatry.2020.3000

This pilot randomized clinical trial examines whether giving a financial incentive in an escalating or deescalating pattern (vs no incentive) to patients receiving antidepressants can enhance medication adherence.


Errors in Results in Abstract and Text and in Figure 2

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(2):224. doi:10.1001/jamapsychiatry.2020.3485

Error in Figure Labels

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(2):224. doi:10.1001/jamapsychiatry.2020.4249
JAMA Psychiatry Masthead

JAMA Psychiatry

Abstract Full Text
free access
JAMA Psychiatry. 2021;78(2):119. doi:10.1001/jamapsychiatry.2020.3110