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Year

Day

February 19, 2020
Viewpoint

The Loss of Social Connectedness as a Major Contributor to Physician Burnout: Applying Organizational and Teamwork Principles for Prevention and Recovery

Abstract Full Text
JAMA Psychiatry. Published online February 19, 2020. doi:10.1001/jamapsychiatry.2019.4800

This Viewpoint discusses social connectedness as a basic human need that when lost leads to burnout and outlines ways health care institutions can apply lessons from team and organizational literature to increase social connectedness and enhance well-being.

Editorial

Is This Where We Stand After Decades of Research to Develop More Personalized Treatments for Depression?

Abstract Full Text
JAMA Psychiatry. Published online February 19, 2020. doi:10.1001/jamapsychiatry.2019.4764

Notice of Retractions: “Association of Posttraumatic Stress Disorder With Reduced In Vivo Norepinephrine Transporter Availability in the Locus Coeruleus” and “Association of In Vivo κ-Opioid Receptor Availability and the Transdiagnostic Dimensional Expression of Trauma-Related Psychopathology” by Alexander Neumeister

Abstract Full Text
JAMA Psychiatry. Published online February 19, 2020. doi:10.1001/jamapsychiatry.2020.0365

These articles by Alexander Neumeister, MD, are being retracted.

Original Investigation

Individual Differences in Response to Antidepressants: A Meta-analysis of Placebo-Controlled Randomized Clinical Trials

Abstract Full Text
JAMA Psychiatry. Published online February 19, 2020. doi:10.1001/jamapsychiatry.2019.4815

This meta-analysis uses data from randomized clinical trials of antidepressants to investigate the assumption of systematic variability in symptomatic response to antidepressants and assesses whether this variability is associated with severity of major depressive disorder, antidepressant class, or year of study publication.

Computational Mechanisms of Effort and Reward Decisions in Patients With Depression and Their Association With Relapse After Antidepressant Discontinuation

Abstract Full Text
JAMA Psychiatry. Published online February 19, 2020. doi:10.1001/jamapsychiatry.2019.4971

This prognostic study examines whether the decision to invest effort for rewards represents a persistent depression process after remission, predicts relapse after remission, or is affected by antidepressant discontinuation.

Research Letter

Cognitive Impairment in Never-Medicated Individuals on the Schizophrenia Spectrum

Abstract Full Text
JAMA Psychiatry. Published online February 19, 2020. doi:10.1001/jamapsychiatry.2020.0001

This cohort study examines cognition in never-medicated individuals at different stages of the illness.

Correction

Data Errors in Results and Table 2

Abstract Full Text
free access
JAMA Psychiatry. Published online February 19, 2020. doi:10.1001/jamapsychiatry.2020.0055

Error in Abstract, Figure 3, and in Captions to Figures 1, 2, and 4

Abstract Full Text
free access
JAMA Psychiatry. Published online February 19, 2020. doi:10.1001/jamapsychiatry.2020.0092
February 12, 2020
Original Investigation

Association of a Reproducible Epigenetic Risk Profile for Schizophrenia With Brain Methylation and Function

Abstract Full Text
JAMA Psychiatry. Published online February 12, 2020. doi:10.1001/jamapsychiatry.2019.4792

This case-control study assesses the association between a blood DNA methylation signature with a reproducible differentiation of patients with schizophrenia from healthy controls and several other major neuropsychiatric disorders.

An Investigation of Psychosis Subgroups With Prognostic Validation and Exploration of Genetic Underpinnings: The PsyCourse Study

Abstract Full Text
JAMA Psychiatry. Published online February 12, 2020. doi:10.1001/jamapsychiatry.2019.4910

This cohort study aims to detect psychosis subgroups and examine their illness courses over 1.5 years and their polygenic scores for schizophrenia, bipolar disorder, major depression disorder, and educational achievement.

Research Letter

Association of High Traditional Masculinity and Risk of Suicide Death: Secondary Analysis of the Add Health Study

Abstract Full Text
JAMA Psychiatry. Published online February 12, 2020. doi:10.1001/jamapsychiatry.2019.4702

This cohort study explores the association between high traditional masculinity and suicide death among US men using data from the Add Health study.

February 5, 2020
Original Investigation

Safety and Efficacy of Exposure-Based Risk Reduction Through Family Therapy for Co-occurring Substance Use Problems and Posttraumatic Stress Disorder Symptoms Among Adolescents: A Randomized Clinical Trial

Abstract Full Text
JAMA Psychiatry. Published online February 5, 2020. doi:10.1001/jamapsychiatry.2019.4803

This randomized clinical trial assesses whether risk reduction through family therapy for adolescents with substance use problems and posttraumatic stress disorder symptoms results in improved outcomes relative to treatment as usual consisting primarily of trauma-focused cognitive behavioral therapy.

Multimodal Categorical and Dimensional Approaches to Understanding Threat Conditioning and Its Extinction in Individuals With Anxiety Disorders

Abstract Full Text
JAMA Psychiatry. Published online February 5, 2020. doi:10.1001/jamapsychiatry.2019.4833

This cross-sectional study uses a threat conditioning and extinction protocol to conduct categorical (DSM-IV–based) and transdiagnostic dimensional (research domain criteria–based) assessments of psychophysiological, neural, and psychometric responses in adults with and without anxiety disorders.

Neuroscience and Psychiatry

Is Hippocampal Replay a Mechanism for Anxiety and Depression?

Abstract Full Text
JAMA Psychiatry. Published online February 5, 2020. doi:10.1001/jamapsychiatry.2019.4788

This article describes research on rodent models that may illuminate connections between hippocampal replay and anxiety and depression in humans.

JAMA Network Insights

Helping Families to Understand and Cope With Psychiatric Disorders in Childhood—Beyond Basic Facts

Abstract Full Text
JAMA Psychiatry. Published online February 5, 2020. doi:10.1001/jamapsychiatry.2019.4812

This article describes means of interacting with children with mental illness and their families in ways that move beyond simple information giving to enhance comprehension, coping, and group decision-making.

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