Chopra et al1 examined the effects of the lipid-lowering 3-hydroxy-3-methylglutaryl–coenzyme A reductase inhibitors (“statins”) on postoperative complications in patients who were naive to these medications. They performed a rigorous systematic review and meta-analysis of 15 studies with almost 2300 patients. The major findings were (1) 44% risk reduction for atrial fibrillation, with a number needed to treat of 6; (2) 47% risk reduction for myocardial infarction, with a number needed to treat of 23; and (3) a 32% reduction in hospital length of stay.