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Invited Commentary
October 2014

Elective Splenectomy for Hematologic Diseases: Can We Predict Complications?

Author Affiliations
  • 1Division of General and Gastrointestinal Surgery, Department of Surgery, Hospital Universitario Virgen de las Nieves, University of Granada, Granada, Spain
JAMA Surg. 2014;149(10):1030. doi:10.1001/jamasurg.2014.310

Splenectomy remains a common procedure for the management of certain benign and malignant hematologic diseases. Laparoscopic splenectomy is associated with better outcomes than open splenectomy and has become the standard approach for these conditions.1-3

In this issue of JAMA Surgery, Bagrodia and colleagues4 report their use of the American College of Surgeons National Surgical Quality Improvement Program database to evaluate clinical and pathologic variables associated with 30-day morbidity and mortality after elective splenectomy for hematologic diseases. They demonstrate that although the postoperative mortality rate is low, splenectomy is associated with substantial morbidity, particularly in patients operated on for malignant disease. Using multivariable logistic regression analysis, the authors identified several clinical variables that were independent predictors of morbidity and mortality.

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