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Clinical Observation
February 1998

Recovery From Lymphocytopenia and Prognosis After Adult Extracorporeal Membrane Oxygenation

Author Affiliations

From the Departments of Thoracic and Cardiovascular Surgery (Drs Kawahito, Misawa, Adachi, Ino, and Fuse) and Clinical Pharmacology (Drs Kobayashi and Fujimura), Jichi Medical School, Tochigi, Japan

Arch Surg. 1998;133(2):216-217. doi:10.1001/archsurg.133.2.216

Extracorporeal circulation severely impairs the host immune system. Also decreases in circulatory lymphocytes correlate with greater degrees of surgical damage. In this study, the pattern of recovery from lymphocytopenia after extracorporeal membrane oxygenation was retrospectively evaluated from a prognostic viewpoint. The results showed that the circulatory lymphocyte count of survivors returned to normal levels within 5 days after their being weaned from extracorporeal membrane oxygenation, while the circulatory lymphocyte count of nonsurvivors remained at low levels. Because it is easy to measure the number of peripheral lymphocytes, the changing pattern of the circulatory lymphocytes might be a simple and reliable prognostic factor after extracorporeal membrane oxygenation.

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