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Correspondence and Brief Communications
June 1998

Problems of Total Parenteral Nutrition—Reply

Arch Surg. 1998;133(6):680. doi:

In reply

Dr Albina has expressed concerns, dismay, and confusion. Dextrose in TPN solutions is dextrose (or D-glucose) (molecular weight, 180.16).1 Because nearly all TPN solutions come from hospital pharmacies, this seemed to be a logical source for centralized information about TPN prescriptions.

Nowhere in the article did we state ". . . the glucose concentration should be limited to less than 4 mg/kg per minute." Our concluding paragraph stated, "Available evidence suggests that the reduction of glucose administration in TPN to less than 4 mg/kg per minute would be beneficial." Concentration does not equal rate of administration. That was the reason for the second survey.

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