There is near unanimity that the preferable treatment of hepatocellular carcinoma or metastatic disease to the liver is operative removal. However, at least three fourths of such patients have contraindications to major hepatic resection, because of either patient factors or local characteristics of the tumor (eg, size, number, location, and the presence of concomitant cirrhosis or extrahepatic disease).
This report from the highly experienced liver group in Villejuif, France, continues their quest in seeking new ways to manage this difficult group of patients. One has to admire their tenacity over the years in taking on this challenge; they clearly are in step with their countrymen who believe that the liver represents the seat of the human soul and accordingly is to be granted special consideration.
Pickleman J. A Comparison of Percutaneous Cryosurgery and Percutaneous Radiofrequency for Unresectable Hepatic Malignancies—Invited Critique. Arch Surg. 2002;137(12):1340. doi:10.1001/archsurg.137.12.1340