Screening Strategies for Pancreatic Cancer in High-Risk Patients: Opportunities to Make a Real Impact But Many Questions and Challenges Still Ahead

In this issue of JAMA Surgery, Del Chiaro and colleagues¹ report the early results of a magnetic resonance imaging (MRI)–based Swedish screening program for asymptomatic patients with an increased risk for familial pancreatic cancer. The goals of this study were to determine whether a high-risk population of patients could be screened in a cost-efficient fashion with a noninvasive screening test and whether this strategy yielded enough premalignant lesions and early cancers to justify the strategy.