[Skip to Content]
[Skip to Content Landing]
Invited Commentary
September 2015

The Role of the Radial Margin: Further Call for Standardization of Colon Cancer Care

Author Affiliations
  • 1Department of Surgery, Johns Hopkins University, Baltimore, Maryland
JAMA Surg. 2015;150(9):898. doi:10.1001/jamasurg.2015.1549

Amri and colleagues1 have provided a retrospective review on the effect of margin positivity on survival among patients with colon cancer. They have found that, although rare, radial margin positivity is associated with a higher recurrence rate, an increased risk of death, and a shorter survival. At first, the concept seems foreign. Generally, it is rare that a colon cancer should have a positive radial margin (unlike rectal cancer, in which the resection margins are limited by bony structures) because most structures adjacent to the colon are resectable. However, in this study,1 a radial positive margin was shown to be an independent predictor of survival.