With advances in chemotherapy, surgical treatment, and postoperative care, the prognosis for children with hepatoblastoma (HBL) has improved significantly during the past 3 decades. The combined use of liver transplantation and chemotherapy is now the preferred treatment option for unresectable HBL.1 In pediatric patients with hepatocellular carcinoma (HCC), transplantation has been associated with improved disease-free survival compared with conventional treatment with chemotherapy and resection, particularly in children with advanced-stage tumors or chronic underlying liver disease.2
Cheng EY, Busuttil RW. Liver Transplantation for Pediatric Hepatoblastoma and Hepatocellular Carcinoma: Out of the Unknown. JAMA Surg. 2015;150(12):1158–1159. doi:10.1001/jamasurg.2015.1875
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