[Skip to Navigation]
Invited Commentary
June 2016

Evaluating Appropriate Blood Transfusion in Cancer Surgery

Author Affiliations
  • 1Surgical Outcomes and Quality Improvement Center, Feinberg School of Medicine, Department of Surgery, Northwestern University, Chicago, Illinois
JAMA Surg. 2016;151(6):525-526. doi:10.1001/jamasurg.2015.5104

The desire to limit blood use in oncologic surgery originated with the finding of increased immunosuppression in patients who received transfusions while undergoing a renal transplant.1 Subsequently, an association was demonstrated between transfusion and increased rates of cancer recurrence and worse overall oncologic prognosis,2 with the results being most pronounced for transabdominal oncologic procedures.3,4