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JAMA Surgery Clinical Challenge
July 2016

Calcified Cyst in the Spleen

Author Affiliations
  • 1Department of General Surgery, Qilu Hospital, Shandong University, Jinan, China
JAMA Surg. 2016;151(7):675-676. doi:10.1001/jamasurg.2016.0060

A man in his mid-50s was referred to our hospital because he had a cystic mass in his spleen that was discovered incidentally during a routine physical examination. He had no history of abdominal trauma, infection, or surgery. A physical examination revealed mild tenderness over the posterior left upper quadrant. A precontrast computed tomographic scan revealed a large, well-defined, cystic mass (7 by 6 cm) with mural calcification in the spleen (Figure 1A), and the cyst was not enhanced in the arterial phase. The laboratory test results, including carcinoembryonic antigen and carbohydrate antigen 19-9 levels, were all within normal ranges, except for a mild increase in the carbohydrate antigen 72-4 level, which was 11.89 U/mL (normal range, 0-6.9 U/mL).

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