A man aged 54 years, who had not seen a physician for nearly 10 years, presented to the emergency department with a 1-month history of generalized weakness and bilateral lower extremity swelling that had progressed to his upper abdomen. Physical examination revealed at least 4 lower extremity edemas and an abdomen that was large, taut, and distended (Figure 1A). A computed tomographic scan of the chest, abdomen, and pelvis was obtained (Figure 1B).