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Comment & Response
September 2017

Use of Adjuvant Chemotherapy After Surgery in Patients With Colon Cancer

Author Affiliations
  • 1Oncology Unit, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy
JAMA Surg. 2017;152(9):895. doi:10.1001/jamasurg.2017.1617

To the Editor We read with interest the article “Chemotherapy Use and Survival Among Young and Middle-Aged Patients With Colon Cancer,” by Manjelievskaia et al1 in JAMA Surgery.

Colorectal cancer (CRC) is the third leading cause of cancer death among young adults aged 20 to 39 years.2 Previous articles have demonstrated that non–stage-adjusted survival rates for CRC in those younger than 30 years are lower than rates in older adults, which is probably because of the higher frequency of stage III and IV CRC at presentation in the younger population.3

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