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Research Letter
December 2017

Association of Intraoperative Radiotherapy in the Treatment of Early-Stage Breast Cancer With Minor Surgical Site Complications in Oncoplastic Breast-Conserving Surgery

Author Affiliations
  • 1Department of Surgery, Section of General Thoracic and Vascular Surgery, Virginia Mason Medical Center, Seattle, Washington
JAMA Surg. 2017;152(12):1180-1182. doi:10.1001/jamasurg.2017.3129

Breast-conserving therapy is a standard treatment option for patients with early-stage breast cancer, as large randomized studies have demonstrated equivalent overall and disease-free survival compared with mastectomy.1,2 Currently, breast-conserving therapy consists of surgical removal of the tumor and axillary staging followed by adjuvant whole-breast radiotherapy (WBRT). Through incorporation of plastic surgery techniques, oncoplastic breast-conserving surgery (OBCS) improves oncologic outcomes while improving cosmesis and reducing rates of postoperative reexcision, complications, and mastectomy.3,4 Breast-conserving therapy requires prolonged treatment owing to daily WBRT, which poses logistical impediments for some patients.