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Comment & Response
April 2018

Optimal Use of Preoperative Imaging in Primary Hyperparathyroidism—Reply

Author Affiliations
  • 1Section of Endocrine Surgery, Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles
  • 2Department of Radiology, Scripps Clinic Medical Group, University of California, San Diego
JAMA Surg. 2018;153(4):394. doi:10.1001/jamasurg.2017.5564

In Reply We thank Collins et al for their interest in our work.1 In their letter, Collins et al point to the discordance rate of 29.9% we reported for parathyroid 4-dimensional computed tomography (4D-CT) as the preoperative localization modality for primary hyperparathyroidism.1 This was compared against the authors’ published data2 of 91% accuracy using a combination of ultrasonography and technetium 99m sestamibi-labeled single-photon emission computed tomography/computed tomography (SPECT/CT).

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