We thought we had it all figured out. After curative resection of colon and rectal cancer, all clinicians know what to do. The National Comprehensive Cancer Network guidelines1 have been very clear and specific. For stage I, clinicians followup with colonoscopy, and for stages II and III, a combination of physical examination, carcinoembryonic antigen, colonoscopy, and computed tomographic scan of the chest abdomen and pelvis at very specific intervals for a total of 5 years. What can go wrong with such a detailed plan?
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Fichera A. Less Is More in Colorectal Cancer Posttreatment Surveillance. JAMA Surg. 2018;153(10):877. doi:10.1001/jamasurg.2018.2066
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