In Reply We thank Uccella et al for their interesting comments regarding our study1 observing a clinically significant increase of 30-day major and minor complications of hysterectomy for uterine fibroids following the US Food and Drug Administration–issued statement against the use of power morcellation. Unfortunately, the lack of data in the American College of Surgeons National Surgical Quality Improvement Program database on the prevalence of unexpected uterine sarcoma did not allow us to estimate mortality rates and surgical complications of minimally invasive hysterectomy with morcellation vs open abdominal hysterectomy.