To the Editor In their article, Margonis et al1 report the role of BRAF V600E mutation as the strongest determinant of prognosis in a large cohort of 849 patients with resected colorectal liver metastases (CRLM). Their findings are consistent with previous reports in the literature,2 including our retrospective series.3
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Moretto R, Cremolini C, Falcone A. BRAF V600E Mutation as a Negative Prognostic Determinant in Resected Colorectal Liver Metastases. JAMA Surg. 2018;153(12):1162–1163. doi:10.1001/jamasurg.2018.3334
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